WO2011090932A3 - A method of treating sinusitis, including chronic sinusitis - Google Patents

A method of treating sinusitis, including chronic sinusitis Download PDF

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Publication number
WO2011090932A3
WO2011090932A3 PCT/US2011/021524 US2011021524W WO2011090932A3 WO 2011090932 A3 WO2011090932 A3 WO 2011090932A3 US 2011021524 W US2011021524 W US 2011021524W WO 2011090932 A3 WO2011090932 A3 WO 2011090932A3
Authority
WO
WIPO (PCT)
Prior art keywords
sinusitis
treating
chronic sinusitis
including chronic
tissue
Prior art date
Application number
PCT/US2011/021524
Other languages
French (fr)
Other versions
WO2011090932A2 (en
Inventor
Howard M. Alliger
Original Assignee
Sinox Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinox Corporation filed Critical Sinox Corporation
Priority to CA2787512A priority Critical patent/CA2787512C/en
Priority to EP11735037.1A priority patent/EP2525802A4/en
Priority to US13/522,570 priority patent/US20130108714A1/en
Publication of WO2011090932A2 publication Critical patent/WO2011090932A2/en
Publication of WO2011090932A3 publication Critical patent/WO2011090932A3/en
Priority to US14/952,221 priority patent/US10201563B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/20Elemental chlorine; Inorganic compounds releasing chlorine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders

Abstract

The present invention relates to a method for treating acute and chronic sinusitis, and in particular, severe chronic sinusitis by exposing affected tissue of the sinus and contiguous tissue in the, nasal cavity and greater oral cavity to effective amounts of chlorine dioxide as a bioactive agent. Compositions and methods of treatment are disclosed herein.
PCT/US2011/021524 2010-01-19 2011-01-18 A method of treating sinusitis, including chronic sinusitis WO2011090932A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2787512A CA2787512C (en) 2010-01-19 2011-01-18 A method of treating sinusitis, including chronic sinusitis
EP11735037.1A EP2525802A4 (en) 2010-01-19 2011-01-18 A method of treating sinusitis, including chronic sinusitis
US13/522,570 US20130108714A1 (en) 2010-01-19 2011-01-18 Method of treating sinusitis, including chronic sinusitis
US14/952,221 US10201563B2 (en) 2010-01-19 2015-11-25 Method of treating sinusitis, including chronic sinusitis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33631910P 2010-01-19 2010-01-19
US61/336,319 2010-01-19
US37223310P 2010-08-10 2010-08-10
US61/372,233 2010-08-10

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/522,570 A-371-Of-International US20130108714A1 (en) 2010-01-19 2011-01-18 Method of treating sinusitis, including chronic sinusitis
US14/952,221 Continuation US10201563B2 (en) 2010-01-19 2015-11-25 Method of treating sinusitis, including chronic sinusitis

Publications (2)

Publication Number Publication Date
WO2011090932A2 WO2011090932A2 (en) 2011-07-28
WO2011090932A3 true WO2011090932A3 (en) 2011-11-17

Family

ID=44307533

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/021524 WO2011090932A2 (en) 2010-01-19 2011-01-18 A method of treating sinusitis, including chronic sinusitis

Country Status (4)

Country Link
US (2) US20130108714A1 (en)
EP (1) EP2525802A4 (en)
CA (1) CA2787512C (en)
WO (1) WO2011090932A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040860B (en) * 2012-11-29 2018-08-14 刘学武 A kind of method starting mammalian stem cell and chlorine dioxide are in the application for preparing drug for starting mammalian stem cell
EP3886812A4 (en) * 2018-11-29 2022-10-19 Yildiz Teknik Universitesi A nasal solution with closed basin natural spring water characteristic and method for obtaining said nasal solution
JP2023522398A (en) * 2020-04-21 2023-05-30 ライフアクティバス プライベート リミテッド Pharmaceutical Compositions of Chlorine for Treatment of Respiratory Viral Infections
WO2022047188A1 (en) * 2020-08-31 2022-03-03 Madray George William Process of using chlorine dioxide for the attenuation and or treatment of coronavirus diseases
US11179415B1 (en) * 2020-12-18 2021-11-23 George William Madray Process of using chlorine dioxide for the attenuation and/or treatment of Coronavirus diseases such as COVID-19 and disabling, treating or attenuating the SARS CoV-2 virus, and its future infective variants

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4084747A (en) * 1976-03-26 1978-04-18 Howard Alliger Germ killing composition and method
US5651996A (en) * 1992-03-04 1997-07-29 Arco Research Co., Inc. Method and compositions for the production of chlorine dioxide
US6039934A (en) * 1998-08-04 2000-03-21 Alliger; Howard Use of xanthan gum for gelling CIO2 and related species
US20040071788A1 (en) * 2002-07-30 2004-04-15 Fuhr Allan H. Nasal hygiene method and composition
US20070196434A1 (en) * 2006-01-20 2007-08-23 Oculus Innovative Sciences, Inc. Methods of preventing or treating sinusitis with oxidative reductive potential water solution

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2623188A (en) * 1987-10-13 1989-05-02 New Generation Products, Inc. Chlorine dioxide germicidal composition
US5489435A (en) * 1993-07-06 1996-02-06 Ratcliff; Perry A. Composition for treatment of abnormal conditions of the epithelium of bodily orifices
US6582682B2 (en) * 2000-10-30 2003-06-24 Noville, Inc. Oral care compositions comprising stabilized chlorine dioxide
US9168318B2 (en) * 2003-12-30 2015-10-27 Oculus Innovative Sciences, Inc. Oxidative reductive potential water solution and methods of using the same
EP2147676A4 (en) * 2007-03-22 2012-02-22 Taiko Pharmaceutical Co Ltd Allergen inactivator
WO2008117767A1 (en) * 2007-03-27 2008-10-02 Taiko Pharmaceutical Co., Ltd. Therapeutic agent for infectious skin or mucosal disease

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4084747A (en) * 1976-03-26 1978-04-18 Howard Alliger Germ killing composition and method
US5651996A (en) * 1992-03-04 1997-07-29 Arco Research Co., Inc. Method and compositions for the production of chlorine dioxide
US6039934A (en) * 1998-08-04 2000-03-21 Alliger; Howard Use of xanthan gum for gelling CIO2 and related species
US20040071788A1 (en) * 2002-07-30 2004-04-15 Fuhr Allan H. Nasal hygiene method and composition
US20070196434A1 (en) * 2006-01-20 2007-08-23 Oculus Innovative Sciences, Inc. Methods of preventing or treating sinusitis with oxidative reductive potential water solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2525802A4 *

Also Published As

Publication number Publication date
US10201563B2 (en) 2019-02-12
EP2525802A2 (en) 2012-11-28
US20160074432A1 (en) 2016-03-17
CA2787512C (en) 2021-10-19
US20130108714A1 (en) 2013-05-02
WO2011090932A2 (en) 2011-07-28
CA2787512A1 (en) 2011-07-28
EP2525802A4 (en) 2013-11-06

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